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AI Virtual Human Twin solutions

Agentic Al-Powered Virtual Human Twins for Clinical Trials

Since September 1, 2025

Utrecht, NL

About services
About DigitaLife

Revolutionizing Drug Development with Agentic AI-Powered Virtual Human Twins for Predictive, Adaptive, and Accelerated Clinical Trials

DigitaLife enables Life Sciences companies to model patient-specific responses using Agentic AI-Powered Virtual Human Twins - reducing trial risk, accelerating timelines, and bringing effective therapies to patients faster.

  • Native Agentic AI-Driven Orchestration Ecosystem
  • Digital-Twin-as-a-Service with High-Fidelity Virtual Human Twins
  • Powered by Agentic AI autonomous multi-agents with strict roles
  • Regulatory-grade Synthetic Control Arms 
Our Solutions

What You’ll Gain

Digital Twin-as-a-Service (DTaaS): High-fidelity Agentic AI-powered Virtual Human Twins to simulate, predict, and optimize clinical development

Study Design Optimization

Re-engineer and optimize study design for patients by learning from historical trial data, testing dose strategies, inclusion/exclusion criteria, endpoints, and enrollment scenarios - improving trial design robustness, feasibility, and probability of success before initiation.

Simulating full trial scenarios

Rapidly run multiple iterations of clinical trials by leveraging therapeutic-specific High-Fidelity Virtual Human Twins and Bayesian statistical models with real-time virtual feedback loops for dose prediction, endpoint optimization and improved efficacy outcomes. This leads to smaller, faster trials, particularly adaptive trials, while improving diversity and augmenting rare disease cohorts where needed.

Right Patient for Recruitment

Identify and stratify ideal patient populations by matching therapies to those most likely to respond, enabling faster recruitment, improved trial outcomes, and more precise, personalized study cohorts.

Synthetic Control Arms

Generate regulatory-aligned virtual control arms to reduce or replace placebo groups, minimizing ethical concerns and patient burden, accelerating enrollment, and improving trial efficiency while maintaining statistical rigor.

Enhancing High-Fidelity Virtual Human Twins

Adaptively learning from Real-World Data via autonomous Agentic AI reasoning loops to build and continuously improve High-Fidelity Virtual Human Twins grounded in a regulatory-grade infrastructure with transparent validation frameworks, statistical control, decision governance and auditability.

Therapeutic Response Prediction

Predict treatment response across diverse patient populations with high accuracy, enabling early validation of efficacy, identification of responders vs non-responders, and better-informed go/no-go decisions before clinical trial execution.

“With AI-powered Virtual Human Twins, every patient’s future can be envisioned. Clinical outcomes unfold before the trial is complete. Smarter choices save time and resources. And the most promising therapies reach patients faster.”

Gene Odle
Team

Meet the experts

Meet the Team accelerating your clinical development path to bring effective therapies to patients faster

Gene Odle

CEO & Co Founder

Rens van der Schoot

CSO & Co Founder

Frans Folkvord

CIO & Co Founder

Jonathan de Bruin

CTO & Co Founder

Simon Klaasen

COO & Co Founder
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DigitaLife Location

Location

Contact the DigitaLife team for more information or share your questions and ideas. We are always happy to meet humans with brilliant ideas!

Address

Vening Meinesz building C, Princetonlaan 6, 3584 CB Utrecht, Netherlands

Phone

Call: +41 79 923 37 00

Email

info@digitalife.ai

Everything You Need to Know

Frequently Asked Questions

What is a digital twin?
A digital twin is a virtual representation of a real-world object, system, or process. It uses real-time data, sensors, and simulations to mirror the physical counterpart, allowing for monitoring, analysis, prediction, and optimization. Digital Twins are widely used in industries like manufacturing, healthcare, smart cities, and energy to improve performance, reduce costs, and support better decision-making. In Healthcare, a digital twin or Virtual Human Twin (VHT) is a patient-specific, dynamic, and digital representation of human health or disease built on data-driven models to predict physical behaviors.
Who is behind DigitaLife?
FwdFaster and Link2Trials are joining forces in the Virtual Human Twin concept. FwdFaster brings its open science approach, leveraging and contributing to open-access and open-source knowledge, while Link2Trials contributes expertise in patient recruitment and adherence services for clinical trials. Together, they combine scientific openness with patient-centered trial support to create Virtual Human Twin solutions that enhance reliability, efficiency, and impact in clinical research.
What is Virtual Human Twin Models for Patient Outcomes?
DigitaLife develops advanced Virtual Human Twin models that simulate individual patient outcomes under various interventions. This capability allows researchers to explore nutritional, behavioral, and therapeutic strategies without requiring large patient cohorts. By modeling mental health trajectories, treatment responses, and disease progression, DigitaLife provides actionable insights that improve study design and clinical decision-making.
What is Synthetic Control Arms & External Comparators?
Through its AI-driven methodologies, DigitaLife generates synthetic control arms based on historical and real-world data. These external comparators reduce the number of patients required in placebo or standard-of-care groups, accelerating recruitment and lowering ethical barriers. This approach ensures statistically robust trial outcomes with smaller, faster studies.
What is Trial Simulation & Data Integration Tools?
DigitaLife offers trial simulation solutions that optimize inclusion and exclusion criteria, refine endpoints, and predict subgroup outcomes. Using integrated datasets — clinical, real-world, and patient-reported — DigitaLife translates complex information into synthetic cohorts. This enables sponsors to test multi-modal interventions in a controlled yet efficient environment, supporting innovative study designs and regulatory submissions.
Stay in the Loop

Make clinical trials faster, smarter, and more patient-centric

Join us in transforming clinical trials and the next generation of evidence-based clinical research through leveraging AI-Powered Virtual Human Twins.